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Anti-inflammatory uye cancer mishonga yakaedzwa muUK sezvinobvira #COVID-19 kurapwa

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6 makore apfuura

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Isu tinoshandisa kusaina kwako kukupa zvirimo munzira dzawakabvumira uye kuvandudza manzwisisiro edu pamusoro pako. Unogona kuzvibvisa chero nguva.

Mishonga miviri inoshandiswa kurapa zvirwere zvinoputika negomarara iri kuedzwa senzira dzekurapa dzevarwere vane COVID-19, maYunivhesiti eBirmingham neOxford akazivisa neChitatu (10 Chikumi), anonyora Paul Sandle.

Mhosva dzakakomba dzeCCIDID-19 dzinofungidzirwa kuti dzakakonzereswa nekuwedzera-kuita kwe immune system, inozivikanwa sedutu recytokine, uye vaongorori vari kuongorora kana mishonga inodzvanyirira zvimwe zvinhu zve immune system inogona kuita basa mukusunga kukurumidza kukwira. yezviratidzo.

Izana Bioscience's Namilumab, monoclonal antibody atove mudanho rekunonoka bvunzo kurapa rheumatoid arthritis uye chirwere chekuzvimba chinonzi ankylosing spondylitis, ndiye wekutanga wevanhu vana muyedzo yeCATALYST.

Inonangana necytokine inonzi GM-CSF, iyo mumazinga asingadzoreki inofungidzirwa kuti ndiyo mutyairi akanyanya uye ane ngozi kuzvimba kwemapapu kunoonekwa muCOVID-19 varwere.

Mushonga uyu uri kutoyedzwa seCCIDID-19 kurapwa muItari.

Mushonga wechipiri, Infliximab (CT-P13), wakagadzirwa neSlough-based Celltrion Healthcare UK, inorwisa-tumor necrosis factor (TNF) therapy. Inoshandiswa kurapa sere autoimmune zvirwere zvinosanganisira rheumatoid arthritis uye irritable bowel syndrome.

Ben Fisher, muongorori wezve kiriniki kubva kuYunivhesiti yeBirmingham, akati: "Uchapupu huripo huri kuratidza basa rakakosha remishonga inorwisa-kuzvimba mudutu recytokine rine chekuita nehutachiona hweCCIDID-19.

"Muchidzidzo cheCATALYST tinotarisira kuratidza nedoro rimwe chete remhando idzi dzemishonga muvarwere vari muchipatara kuti tinokwanisa kunonoka kana kudzivirira kukurumidza kuparara mukutarisirwa kwakanyanya uye zvinodiwa zvekupinda mhepo muboka revarwere rakakosha."

Mimwe mishonga yechirwere che autoimmune iri kuongororwa kuti inokwanisa kudzikamisa dutu re cytokine mumiyedzo inosanganisira Regeneron neSanofi's Kevzara, Roche's Actemra pamwe neMorphosys neGlaxoSmithKline's otilimab.

Takeda yekuJapan ine strategic equity stake in Izana.

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